Deep Hamburger Sausage Pepperoni is a delightful fusion of savory meats and gooey cheeses encased in a flaky pie crust. This recipe is not just about combining ingredients; it’s about creating a dish that brings comfort and satisfaction. Each slice of this delicious pie delivers a burst of flavor, making it the perfect choice for family dinners or gatherings with friends. The blend of hamburger sausage and pepperoni creates a unique flavor profile that elevates a classic comfort food experience while staying true to its roots. Let’s dive into this incredible ultimate recipe that will surely become a favorite in your household!

Why You’ll Love This Deep Hamburger Sausage Pepperoni
This savory sausage recipe is not just another pie; it’s an experience! Here are six reasons why you’ll adore this dish:
- It’s a crowd-pleaser, perfect for parties or family gatherings.
- The combination of hamburger sausage with pepperoni adds a rich flavor that is hard to resist.
- It’s a unique twist on traditional meat pies, making it a standout dish.
- Simple preparation, making it a great choice for busy weeknights.
- Loaded with cheesy goodness, thanks to mozzarella and cheddar.
- Can be customized with your favorite ingredients to create your own version!
This dish is an American classic, fitting perfectly into the Dinner Ideas category while being a healthy option with its low-calorie ingredients.
Ingredients for Deep Hamburger Sausage Pepperoni
Gather these items:
- 1 pre-made pie crust (store-bought or homemade)
- 1 pound ground beef
- ½ pound Italian sausage, casing removed
- ½ cup pepperoni slices
- 1 cup shredded mozzarella cheese
- 1 cup shredded cheddar cheese
- 1 small onion, diced
- 2 cloves garlic, minced
- 1 teaspoon Italian seasoning
- ½ teaspoon salt
- ½ teaspoon black pepper
- 2 large eggs
- ¼ cup milk
How to Make Deep Hamburger Sausage Pepperoni Step-by-Step
- Step 1: Preheat your oven to 375°F (190°C).
- Step 2: In a large skillet over medium heat, cook the ground beef and Italian sausage until browned. Drain any excess grease.
- Step 3: Stir in the diced onion and minced garlic. Cook until the onion is translucent.
- Step 4: Add Italian seasoning, salt, and black pepper to the meat mixture. Mix well and remove from heat.
- Step 5: Fold in the pepperoni slices, ensuring they are evenly distributed throughout the meat mixture.
- Step 6: In a separate bowl, combine the mozzarella and cheddar cheese. Reserve a small amount for topping the pie.
- Step 7: In another bowl, whisk together the eggs and milk. Stir this mixture into the meat mixture, followed by the cheese mixture. Combine until well blended.
- Step 8: Place the pre-made pie crust into a pie dish. Pour the meat and cheese mixture into the crust, spreading it evenly.
- Step 9: Sprinkle the reserved cheese on top for a deliciously cheesy finish.
- Step 10: Bake in the preheated oven for 45 minutes or until the crust is golden brown and the cheese is bubbly.
- Step 11: Remove the pie from the oven and let it cool for 15 minutes before slicing.
- Step 12: Cut into wedges and serve warm.
Pro Tips for the Perfect Deep Hamburger Sausage Pepperoni
Keep these in mind:
- Let the pie cool for better slicing.
- Use your favorite cheese blend for variation.
- For an extra kick, try adding some jalapeños or hot sauce to the meat mixture!
Best Ways to Serve Deep Hamburger Sausage Pepperoni
This dish pairs wonderfully with a fresh side salad or steamed vegetables to balance the savory flavors. You can also serve it with a side of marinara sauce for dipping, creating a delightful sausage and pepperoni dish.

How to Store and Reheat Deep Hamburger Sausage Pepperoni
To store, wrap any leftover pie in plastic wrap and place it in the refrigerator. It can last up to 3 days. When ready to enjoy again, reheat in the oven at 350°F (175°C) until warmed through. This makes it perfect for meal prep!
Frequently Asked Questions About Deep Hamburger Sausage Pepperoni
What’s the secret to perfect Deep Hamburger Sausage Pepperoni?
The secret to the perfect pie lies in not overcooking the meat. You want it browned but not dry, ensuring a juicy filling that complements the deep-fried sausage aspect of the dish.
Can I make Deep Hamburger Sausage Pepperoni ahead of time?
Absolutely! You can prepare the pie ahead of time and store it in the fridge before baking. Just pop it in the oven when you’re ready to serve for a delicious, fresh meal.
How do I avoid common mistakes with Deep Hamburger Sausage Pepperoni?
Avoid common pitfalls by ensuring your crust is fully cooked before adding the filling. Also, don’t skip cooling the pie before slicing; it helps maintain the structure of the filling.
Variations of Deep Hamburger Sausage Pepperoni You Can Try
Feel free to explore some pepperoni sausage variations or experiment with different types of fillings, such as adding mushrooms or bell peppers. You could even try a spicier sausage for a different flavor profile!

For more delicious recipes, check out our Cheesy Hamburger Potato Soup or Creamy Tuscan Scallops. If you’re looking for a quick meal, our One Pan Cheesy Ranch is a great option!
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Deep Hamburger Sausage Pepperoni: 8 Irresistible Reasons
- Total Time: 1 hour
- Yield: 8 servings 1x
- Diet: Low Calorie
Description
Deep Hamburger Sausage & Pepperoni Pie is an incredible ultimate recipe that combines savory meats and cheeses in a delicious pie crust.
Ingredients
- 1 pre-made pie crust (store-bought or homemade)
- 1 pound ground beef
- ½ pound Italian sausage, casing removed
- ½ cup pepperoni slices
- 1 cup shredded mozzarella cheese
- 1 cup shredded cheddar cheese
- 1 small onion, diced
- 2 cloves garlic, minced
- 1 teaspoon Italian seasoning
- ½ teaspoon salt
- ½ teaspoon black pepper
- 2 large eggs
- ¼ cup milk
Instructions
- Preheat your oven to 375°F (190°C).
- In a large skillet over medium heat, cook the ground beef and Italian sausage until browned. Drain any excess grease.
- Stir in the diced onion and minced garlic. Cook until the onion is translucent.
- Add Italian seasoning, salt, and black pepper to the meat mixture. Mix well and remove from heat.
- Fold in the pepperoni slices, ensuring they are evenly distributed throughout the meat mixture.
- In a separate bowl, combine the mozzarella and cheddar cheese. Reserve a small amount for topping the pie.
- In another bowl, whisk together the eggs and milk. Stir this mixture into the meat mixture, followed by the cheese mixture. Combine until well blended.
- Place the pre-made pie crust into a pie dish. Pour the meat and cheese mixture into the crust, spreading it evenly.
- Sprinkle the reserved cheese on top for a deliciously cheesy finish.
- Bake in the preheated oven for 45 minutes or until the crust is golden brown and the cheese is bubbly.
- Remove the pie from the oven and let it cool for 15 minutes before slicing.
- Cut into wedges and serve warm.
Notes
- Let the pie cool for better slicing.
- Use your favorite cheese blend for variation.
- Prep Time: 15 minutes
- Cook Time: 45 minutes
- Category: Main Dish
- Method: Baking
- Cuisine: American
Nutrition
- Serving Size: 1 slice
- Calories: 350 kcal
- Sugar: 1g
- Sodium: 800mg
- Fat: 20g
- Saturated Fat: 8g
- Unsaturated Fat: 10g
- Trans Fat: 0g
- Carbohydrates: 20g
- Fiber: 1g
- Protein: 22g
- Cholesterol: 150mg